p53 Activator 14
p53 Activator 14 (Compound 7A) is a derivative of Neratinib (HY-32721), that induces DNA damage, activates p53, and inhibits the proliferation of multi cancer cells (IC50=7.21 μM for HCT116 cell). p53 Activator 14 inhibits the adhesion, migration and invasion of HCT116, arrests the cell cycle, and induces apoptosis. p53 Activator 14 inhibits angiogenesis and exhibits antitumor efficacy in chick chorioallantoic membrane (CAM) model.
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- CAS No.: 2922588-44-9
- Formule: C28H29ClN4O3
- Masse moléculaire:505.01
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 2922588-44-9
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Masse moléculaire 505.01
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Formule C28H29ClN4O3
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SMILES
O=C(C1=CC=C(CN2CCN(CC2)C(C3CC3)=O)C=C1)NC4=CC=C(C(Cl)=C4)OCC5=NC=CC=C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p53 Activator 14 Related Classifications
HY-170591 Related Classifications
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