PDE5-IN-10
PDE5-IN-10 (compound 4b) is a potent PDE5 inhibitor with an IC50 of 20 nM. PDE5-IN-10 improves in vitro microsomal stability (t1/2 = 44.6 min) as well as excellent efficacy in restoring long-term potentiation. PDE5-IN-10 can be used for Alzheimer’s disease (AD) research.
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- Formule: C21H20N4O2
- Masse moléculaire:360.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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PDE5 20 nM (IC50) |
Chemical Information
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Masse moléculaire 360.41
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Formule C21H20N4O2
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SMILES
N#CC1=CC(C2CC2)=C3N=CC(CO)=C(NCC4=CC=C(OC)N=C4)C3=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)