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Cat. No.: HY-160006

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PIM-IN-2

PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC₅₀ = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors.

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CAS No.: 1006699-45-1
Formule: C₁₉H₂₂N₄O₂
Masse moléculaire:338.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

PIM-IN-2 Chemical Structure

CAS No.: 1006699-45-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

PIM-IN-2 (Pim-2) is a Pim kinases inhibitor (IC₅₀ = 25 nM). PIM-IN-2 promotes cell survival, is antiapoptotic, and has exhibited an elevated level of expression in a variety of human tumors^[1].

IC₅₀ & Target

PIM2

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Chemical Information

CAS No. 1006699-45-1
Masse moléculaire 338.40
Formule C₁₉H₂₂N₄O₂
SMILES

OC(/C=C/C1=CC=CC(C2=NC(NCC3CCNCC3)=CN=C2)=C1)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Qian K, et al. Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode [J]. Journal of medicinal chemistry, 2009, 52(7): 1814-1827. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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PIM-IN-2

Voir tous les produits spécifiques à Isoform Pim

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PIM-IN-2 Related Classifications

HY-160006 Related Classifications