Some observations on the estimation of 3-methoxytyramine in brain tissue

  • Br J Pharmacol. 1971 Aug;42(4):505-11. doi: 10.1111/j.1476-5381.1971.tb07136.x.
H C Guldberg ,  D F Sharman ,  P R Tegerdine
PMID: 4398930 DOI: 10.1111/j.1476-5381.1971.tb07136.x
Abstract

1. A new method for the estimation of 4-hydroxy-3-methoxyphenylethylamine (3-methoxytyramine) in brain tissue is described. This is based on the formation of a fluorescent derivative by oxidation with potassium ferricyanide in ammonium hydroxide solution.2. The effects of some drugs on the concentration of 3-methoxytyramine in the brain are reported.3. The significance of changes in the striatal concentration of 3-methoxytyramine is discussed.

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