country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-148387

Copy Link Print Information

SARS-CoV-2-IN-35

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M ^pro inhibitor with a K_i value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2757763-47-4
Formule: C₂₉H₃₄F₃N₅O₅S
Masse moléculaire:621.67

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

SARS-CoV-2-IN-35 Chemical Structure

CAS No.: 2757763-47-4

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M ^pro inhibitor with a K_i value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19^[1].

In Vivo

SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Wistar-Han rats^[1]
Dosage:

10 mg/kg
Administration:

Oral administration
Result:

Had oral F of 33 %.

Chemical Information

CAS No. 2757763-47-4
Masse moléculaire 621.67
Formule C₂₉H₃₄F₃N₅O₅S
SMILES

O=C(C1=NC2=CC=CC=C2S1)[C@H](C[C@H]3C(NCC3)=O)NC([C@@H]4[C@]5([H])[C@@](CN4C([C@H](C(C)C)NC(C(F)(F)F)=O)=O)([H])C5(C)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Owen DR, et, al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science. 2021 Dec 24;374(6575):1586-1593. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis