SB-611812
Based on 1 Customer Validation
SB-611812 is a urotensin II receptor (UTR) antagonist with the potential in the research of cardiovascular disease.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.92%
- CAS No.: 345892-71-9
- Formule: C17H16Cl3F3N2O3S
- Masse moléculaire:491.74
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
Chemical Information
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CAS No. 345892-71-9
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Appearance Solid
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Masse moléculaire 491.74
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Formule C17H16Cl3F3N2O3S
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Color Light yellow to yellow
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SMILES
O=S(NC1=CC=C(C(OCCN(C)C)=C1)Cl)(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 16.67 mg/mL (33.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Rakowski E, et al. A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blocker. J Mol Cell Cardiol. 2005 Nov;39(5):785-91. [Content Brief]
[2]. Cosenzi A. Non peptidic urotensin II antagonists: perspectives for a new class of drugs. Cardiovasc Hematol Agents Med Chem. 2008 Apr;6(2):80-91. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0336 mL | 10.1680 mL | 20.3360 mL | 50.8399 mL |
| 5 mM | 0.4067 mL | 2.0336 mL | 4.0672 mL | 10.1680 mL | |
| 10 mM | 0.2034 mL | 1.0168 mL | 2.0336 mL | 5.0840 mL | |
| 15 mM | 0.1356 mL | 0.6779 mL | 1.3557 mL | 3.3893 mL | |
| 20 mM | 0.1017 mL | 0.5084 mL | 1.0168 mL | 2.5420 mL | |
| 25 mM | 0.0813 mL | 0.4067 mL | 0.8134 mL | 2.0336 mL | |
| 30 mM | 0.0678 mL | 0.3389 mL | 0.6779 mL | 1.6947 mL |