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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
MCC
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "MCC" in MCE Product Catalog:
486
486 Publications Verification
Synonyms: CP-456773; CRID3
Target:
Domaines de recherche:
MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
486
486 Publications Verification
Synonyms: CP-456773 sodium; CRID3 sodium salt
Target:
Domaines de recherche:
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
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1 Cited Publications
Synonyms: Lys-Nε-MCC-DM1
Target:
Domaines de recherche:
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer .
Synonyms: MCC7840
Target:
Domaines de recherche:
Emlenoflast (MCC7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast can be used for the research of inflammatory diseases .
Target:
Domaines de recherche:
MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues .
Target:
Domaines de recherche:
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 .
Cat. No.: HY-174279
CAS No.: 3052836-65-1
Target:
Domaines de recherche:
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment .
Synonyms: MCC-555; Isaglitazone
Target:
Domaines de recherche:
Netoglitazone (MCC-555) is an orally active PPARγ ligand with an EC50 of 8 μM. Netoglitazone mediates cell type-specific functional regulation, and modulates the transcriptional activity of PPARγ as a full agonist, partial agonist or antagonist. Netoglitazone induces adipogenesis, inhibits osteoblastogenesis, alters the weight of extramedullary fat depots and enhances insulin sensitivity. Netoglitazone reduces blood glucose levels. Netoglitazone can be used in research related to type 2 diabetes and non-insulin-dependent diabetes mellitus .
Synonyms: MCC7840 sodium
Target:
Domaines de recherche:
Emlenoflast (MCC7840) sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM. Emlenoflast sodium can be used for the research of inflammatory diseases .
Cat. No.: HY-P991661
CAS No.: 1607838-85-6
Domaines de recherche:
Synonyms: MCC-135
Target:
Domaines de recherche:
Caldaret is an intracellular Ca 2+ handling modulator that acts through reverse mode Na +/Ca 2+ exchanger inhibition.
Cat. No.: HY-101982A
Pureté: 98.18%
Synonyms: (Rac)-Lys-Nε-MCC-DM1
Target:
Domaines de recherche:
(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1 .
Synonyms: LY582563; MCC-478
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect .
Cat. No.: HY-141143
CAS No.: 2504147-59-3
Target:
Domaines de recherche:
MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-128959
CAS No.: 721945-30-8
Target:
Domaines de recherche:
MCC-Modified Daunorubicinol is a drug-Linker conjugates for ADC, which is composed of Modified Daunorubicinol (DNA topoisomerase II inhibitor) and MCC (ADC linker) linked .
Cat. No.: HY-W800787
CAS No.: 384847-49-8
18:1 PE MCC is a reactive phospholipid containing a maleimide group. 18:1 PE MCC forms covalent bonds with thiol-modified chondroitin sulfate (CS) via thiol-maleimide reaction, and anchors CS to the surface of lipid membranes. 18:1 PE MCC is applicable to glycocalyx model construction and lipid membrane biophysics research .
Cat. No.: HY-12815R
CAS No.: 210826-40-7
Synonyms: CP-456773 (Standard); CRID3 (Standard)
Domaines de recherche:
MCC950 (Standard) is the analytical standard of MCC950. This product is intended for research and analytical applications. MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
Cat. No.: HY-119306
CAS No.: 181238-67-5
Target:
Domaines de recherche:
MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent .
Cat. No.: HY-14936
CAS No.: 187602-11-5
Synonyms: MCC-977
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Domaines de recherche:
Sofigatran (MCC-977) is an orally active factor IIa (thrombin) inhibitor, acts as an anticoagulant. Sofigatran is used for the research of cardiovascular disease .
Cat. No.: HY-W800786
CAS No.: 384832-87-5
Synonyms: N-MCC-PE
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
