STING-IN-12
STING-IN-12 (compound Y2) is an inhibitor of STING. STING-IN-12 inhibits IFNβ gene expression (IC50=0.75μM) induced by SR717. STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and MSA-2-induced STING pathway activation in vivo in mice.
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- Formule: C15H13F3N2O5
- Masse moléculaire:358.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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Masse moléculaire 358.27
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Formule C15H13F3N2O5
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SMILES
O=C(NC1=CC=C(OCCCC(F)(F)F)C=C1)C2=CC=C([N+]([O-])=O)O2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)