24589-78-4
Chemical Structure
2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide
Synonym(s): N-Methyl-n-trimethylsilyltrifluoroacetamide
- CAS No.: 24589-78-4
- Formula:C6H12F3NOSi
- Molecular Weight:199.25
IUPAC Name: 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)acetamide
InChIKey: MSPCIZMDDUQPGJ-UHFFFAOYSA-N
SMILES: O=C(N(C)[Si](C)(C)C)C(F)(F)F
Biological Activity: 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product commonly used for silylation reactions in analyticalchemistry. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in the derivatization step of metabolomics analysis with gas chromatography/mass spectrometry (GC/MS) or as a derivatization reagent in GC with flame ionization detection analysis. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in research for studying Tamoxifen (HY-13757A) resistant breast cancer cells and other disease pathways[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide | 98.79% | 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product commonly used for silylation reactions in analyticalchemistry. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in the derivatization step of metabolomics analysis with gas chromatography/mass spectrometry (GC/MS) or as a derivatization reagent in GC with flame ionization detection analysis. 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide can be used in research for studying Tamoxifen (HY-13757A) resistant breast cancer cells and other disease pathways. | ||||||||||||||||||||
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Similarity Score 0.73
HY-Y0147(Trifluoromethyl)trimethylsilane -
Similarity Score 0.70
HY-W089645SN-Methyl-N-(trimethylsilyl)trifluoroacetamide-d9 -
Similarity Score 0.68
HY-W105853Ammonium trifluoroacetate -
Similarity Score 0.68
HY-207552,2,2-Trifluoro-N-(2-hydroxyethyl)acetamide -
Similarity Score 0.67
HY-W017049RSodium trifluoroacetate (Standard) -
Similarity Score 0.67
HY-W017049SSodium trifluoroacetate-13C2 -
Similarity Score 0.67
HY-W754811Trifluoroacetic acid-13C sodium -
Similarity Score 0.66
HY-W016948TFA-Gly-OH -
Similarity Score 0.66
HY-138322N-trifluoroacetyl-β-alanyl chloride -
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References
- [1]. Böröczky, K., et al., (2006). Cluster analysis as selection and dereplication tool for the identification of new natural compounds from large sample sets. Chemistry & biodiversity, 3(6), 622–634. [Content Brief]
- [2]. Müller, C., et al., (2019). A gas chromatography-mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis. Nature protocols, 14(8), 2546–2570. [Content Brief]
- [3]. Mishra, A., et al., (2024). Comparative metabolomics of MCF-7 and MCF-7/TAMR identifies potential metabolic pathways in tamoxifen resistant breast cancer cells. American journal of translational research, 16(4), 1337–1352. [Content Brief]
