4825-86-9
4825-86-9
Chemical Structure
Ochratoxin B
- CAS No.: 4825-86-9
- Formula:C20H19NO6
- Molecular Weight:369.37
IUPAC Name: ((S)-8-hydroxy-3-methyl-1-oxoisochromane-7-carbonyl)-L-phenylalanine
InChIKey: DAEYIVCTQUFNTM-NHYWBVRUSA-N
SMILES: O=C1O[C@H](CC2=C1C(O)=C(C=C2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C
Biological Activity: Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ochratoxin B | 99.90% | Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos. | ||||||||||||||||||||
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Ochratoxin B (Standard) | ≥98% | Ochratoxin B (Standard) is the analytical standard of Ochratoxin B (HY-N6786). This product is intended for research and analytical applications. Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos. | ||||||||||||||||||||
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Ochratoxin B13C20 | Ochratoxin B-13C20 is 13C-labeled Ochratoxin B (HY-N6786). Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A (HY-N6788). Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos. | |||||||||||||||||||||
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References
- [1]. Knasmüller S, et al. Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment. Nutr Cancer. 2004;50(2):190-7. [Content Brief]
- [2]. O'Brien E, et al. Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system. Birth Defects Res B Dev Reprod Toxicol. 2005 Oct;74(5):417-23. [Content Brief]
- [3]. Dietrich DR, et al. Species- and sex-specific renal cytotoxicity of ochratoxin A and B in vitro. Exp Toxicol Pathol. 2001 Jun;53(2-3):215-25. [Content Brief]
- [4]. Csenki Z, et al. The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food Chem Toxicol. 2021 Dec;158:112674. [Content Brief]
- [5]. Mally A, et al. Biotransformation and nephrotoxicity of ochratoxin B in rats. Toxicol Appl Pharmacol. 2005 Aug 1;206(1):43-53. [Content Brief]
- [6]. Størmer FC, et al. Metabolism of ochratoxin B and its possible effects upon the metabolism and toxicity of ochratoxin A in rats. Appl Environ Microbiol. 1985 May;49(5):1108-12. [Content Brief]
