863202-33-9
863202-33-9
Chemical Structure
A3AR antagonist 3
- CAS No.: 863202-33-9
- Formula:C17H18N6
- Molecular Weight:306.37
IUPAC Name: N6-((1R,4S,5r)-bicyclo[2.1.1]hexan-5-yl)-N2-phenyl-9H-purine-2,6-diamine
InChIKey: WCAVIMDYDZJYPK-PTEHBNRSSA-N
SMILES: [H][C@@]12[C@H]([C@@](C2)([H])CC1)NC3=C4N=CNC4=NC(NC5=CC=CC=C5)=N3
Biological Activity: A3AR antagonist 3 (compound 21) is a selective A3 adenosine receptor (A3AR) antagonist with a Ki of 37 nM. A3AR antagonist 3 shows >60-fold selectivity in comparison to A1 and A2A adenosine receptors[1].
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A3AR antagonist 3 | A3AR antagonist 3 (compound 21) is a selective A3 adenosine receptor (A3AR) antagonist with a Ki of 37 nM. A3AR antagonist 3 shows >60-fold selectivity in comparison to A1 and A2A adenosine receptors. | |||||||||||||||||||||
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