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Art. -Nr.: HY-186235

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3-Hydroxydecanoyl-NAC

3-Hydroxydecanoyl-NAC is a substrate mimetic of the bacterial fatty acid biosynthetic pathway, and exhibits activity against FabA and FabG of Pseudomonas aeruginosa. 3-Hydroxydecanoyl-NAC acts as a stable mimetic of acyl carrier protein-linked fatty acids, which are key intermediates in the bacterial FASII pathway. 3-Hydroxydecanoyl-NAC serves as a substrate for Pseudomonas aeruginosa FabA, enabling the measurement of the dehydration activity of this enzyme.

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Formel: C₁₅H₂₉NO₃S
Molecular Weight:303.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Hydroxydecanoyl-NAC Chemical Structure

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

3-Hydroxydecanoyl-NAC (0.4 mM) functions as a substrate for Pseudomonas aeruginosa FabA in a direct UV absorbance assay, enabling measurement of the enzyme's dehydration activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 303.46
Formel C₁₅H₂₉NO₃S
SMILES

CC(NCCSC(CC(O)CCCCCCCC)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Moynié L, et al. A Substrate Mimic Allows High-Throughput Assay of the FabA Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas aeruginosa FabA. Journal of molecular biology. 2016 Jan 16;428(1):108-120. [Content Brief]

[2]. Schwab J M, et al. Stereochemical course of the hydration reaction catalysed by β-hydroxydecanoylthioester dehydrase[J]. Journal of the Chemical Society, Chemical Communications, 1986 (4): 357-358.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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