Chitinase-IN-2
Based on 1 publication(s) in Google Scholar
Chitinase-IN-2 is an insecticide that can inhibit the activity of chitinase and N-acetylhexosaminidase, with inhibition percentages of 98% and 92% at concentrations of 50 μM and 20 μM, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.38%
- CAS. Nr.: 1579991-63-1
- Formel: C20H21N5O2S
- Molecular Weight:395.48
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Lösungsmittel & Löslichkeit
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Publications Citing Use of MedChemExpress (MCE) Chitinase-IN-2
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Biologische Aktivität
Chemical Information
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CAS. Nr. 1579991-63-1
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Appearance Oil
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Molecular Weight 395.48
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Formel C20H21N5O2S
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Color Yellow to orange
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SMILES
O=C(C1=CC=CC2=C1C3=CC=C2N(C)C)N(CCNCC4=NN=C(C)S4)C3=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Neuroscience
Chitinase1 contributed to a potential protection via microglia polarization and Aβ oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments. [Abstract]2017 Jul 4:355:61-70. PMID: 28499970
Chitinase-IN-2 purchased from MedChemExpress. Usage Cited in: Neuroscience. 2017 Jul 4:355:61-70. [Abstract]
Measurement of Aβ oligomers by immunohistochemical staining (×200) and western blot in experimental animals. Whether in the hippocampus (A) or cortex (B), there are much more Aβ oligomers in theAD rats compared to controls (p<0.05). Compared with the AD group, expression of Aβ oligomers in the cortex and hippocampus following chitinase treatment in AD rats is reduced (p<0.05), while the chitinase inhibitor (chitinase-IN-2) increases the Aβ oligomer expression (p<0.05)
Lösungsmittel & Löslichkeit
DMSO : ≥ 53 mg/mL (134.01 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 50 mg/mL (126.43 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O / DMSO | 1 mM | 2.5286 mL | 12.6429 mL | 25.2857 mL | 63.2143 mL |
| 5 mM | 0.5057 mL | 2.5286 mL | 5.0571 mL | 12.6429 mL | |
| 10 mM | 0.2529 mL | 1.2643 mL | 2.5286 mL | 6.3214 mL | |
| 15 mM | 0.1686 mL | 0.8429 mL | 1.6857 mL | 4.2143 mL | |
| 20 mM | 0.1264 mL | 0.6321 mL | 1.2643 mL | 3.1607 mL | |
| 25 mM | 0.1011 mL | 0.5057 mL | 1.0114 mL | 2.5286 mL | |
| 30 mM | 0.0843 mL | 0.4214 mL | 0.8429 mL | 2.1071 mL | |
| 40 mM | 0.0632 mL | 0.3161 mL | 0.6321 mL | 1.5804 mL | |
| 50 mM | 0.0506 mL | 0.2529 mL | 0.5057 mL | 1.2643 mL | |
| 60 mM | 0.0421 mL | 0.2107 mL | 0.4214 mL | 1.0536 mL | |
| 80 mM | 0.0316 mL | 0.1580 mL | 0.3161 mL | 0.7902 mL | |
| 100 mM | 0.0253 mL | 0.1264 mL | 0.2529 mL | 0.6321 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Chitinase-IN-2 Related Classifications
HY-18599 Related Classifications
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