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Art. -Nr.: HY-159093

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Antitumor agent-178

Antitumor agent-178 (compound 4 h) is a potent and selective GSCs inhibitor. Antitumor agent-178 has the potential for the research of cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₇H₄₁BrO₅
Molecular Weight:525.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Antitumor agent-178 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Antitumor agent-178 (compound 4 h) is a potent and selective GSCs inhibitor. Antitumor agent-178 has the potential for the research of cancer^[1].

In Vitro

Antitumor agent-178 (compound 4 h) (0-100 µM; 48 h) inhibits GBM43 cell growth with GI₅₀s of 0.49, 0.16 µM at PH 7.5 and PH 6.5, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

GBM43 cells
Concentration:

10 nM-100 µM
Incubation Time:

48 h
Result:

Inhibited cell growth with GI₅₀s of 0.49, 0.16 µM at PH 7.5 and PH 6.5, respectively.

Chemical Information

Molecular Weight 525.52
Formel C₂₇H₄₁BrO₅
SMILES

C/C(C)=C/[C@H](O1)C[C@@H]([C@@]21CC[C@@]3(C[C@H]4[C@@H](/C([C@@H](C[C@@H]23)O)=C/OCCBr)C(C[C@]4(O)C)=O)C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Maslivetc VA, et al. Ophiobolin A derivatives with enhanced activities under tumor-relevant acidic conditions. Bioorg Med Chem Lett. 2024 Jun 26;110:129863. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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