Bromo-PEG3-CH2-Boc
Based on 1 Customer Validation
Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 2100306-71-4
- Formel: C12H23BrO5
- Molecular Weight:327.21
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2100306-71-4
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Appearance Liquid (Density: 1.246 g/cm3)
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Molecular Weight 327.21
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Formel C12H23BrO5
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)COCCOCCOCCBr
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (305.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0561 mL | 15.2807 mL | 30.5614 mL | 76.4035 mL |
| 5 mM | 0.6112 mL | 3.0561 mL | 6.1123 mL | 15.2807 mL | |
| 10 mM | 0.3056 mL | 1.5281 mL | 3.0561 mL | 7.6404 mL | |
| 15 mM | 0.2037 mL | 1.0187 mL | 2.0374 mL | 5.0936 mL | |
| 20 mM | 0.1528 mL | 0.7640 mL | 1.5281 mL | 3.8202 mL | |
| 25 mM | 0.1222 mL | 0.6112 mL | 1.2225 mL | 3.0561 mL | |
| 30 mM | 0.1019 mL | 0.5094 mL | 1.0187 mL | 2.5468 mL | |
| 40 mM | 0.0764 mL | 0.3820 mL | 0.7640 mL | 1.9101 mL | |
| 50 mM | 0.0611 mL | 0.3056 mL | 0.6112 mL | 1.5281 mL | |
| 60 mM | 0.0509 mL | 0.2547 mL | 0.5094 mL | 1.2734 mL | |
| 80 mM | 0.0382 mL | 0.1910 mL | 0.3820 mL | 0.9550 mL | |
| 100 mM | 0.0306 mL | 0.1528 mL | 0.3056 mL | 0.7640 mL |
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