GLIPR2 - GLI pathogenesis related 2 Gene

Also Known as GAPR1; GAPR-1; C9orf19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 152007

About GLIPR2

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:36,136,536-36,163,913 (from NCBI)

This gene has 5 transcripts (splice variants), 211 orthologues and 13 paralogues. Broad expression in lung (RPKM 23.8), appendix (RPKM 20.8) and 24 other tissues.

Summary

Enables protein homodimerization activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of epithelial cell migration; and positive regulation of epithelial to mesenchymal transition. Located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

GLIPR2 Products (6)

mRNA Protein Name
NM_001287010.2 NP_001273939.1 Golgi-associated plant pathogenesis-related protein 1 isoform b
NM_001287011.2 NP_001273940.1 Golgi-associated plant pathogenesis-related protein 1 isoform c
NM_001287012.2 NP_001273941.1 Golgi-associated plant pathogenesis-related protein 1 isoform d
NM_001287013.2 NP_001273942.1 Golgi-associated plant pathogenesis-related protein 1 isoform e
NM_001287014.2 NP_001273943.1 Golgi-associated plant pathogenesis-related protein 1 isoform f
NM_022343.4 NP_071738.1 Golgi-associated plant pathogenesis-related protein 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
15123429 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
23516513 GOA
involved in positive regulation of epithelial cell migration IDA
IDA: Inferred from direct assay
23516513 GOA
involved in positive regulation of epithelial to mesenchymal transition IDA
IDA: Inferred from direct assay
23516513 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
11865038 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GLIPR2 Protein Structure

CAP

CAP: Cysteine-rich secretory protein family (14 - 131)

  • 0
  • 100
  • 154 a.a.
Protein Preferred Names Protein Names

Golgi-associated plant pathogenesis-related protein 1

  • 17kD fetal brain protein

Related Diseases

Diseases Alias
Necatoriasis

  • Miner'S Anaemia

  • Negro Cachexia

  • Dochmiasis

  • Ground Itch Disease

  • Brickmaker'S Chlorosis

  • Coolie Itch Anaemia

  • Cachexia Aquosa

  • Dew Itch Anaemia

  • Brickmaker'S Anaemia

  • Tunnel Worker'S Anaemia

  • Egyptian Anaemia

  • Tunnel Worker'S Disease

  • Miner'S Cachexia

  • Greisinger Disease

  • Tropical Chlorosis

  • Egyptian Chlorosis

  • Tunnel Anaemia

  • Dochmiosis

  • Necatorosis

  • African Cachexia

  • Water Itch Anaemia

  • Infection Due To Necator Americanus

  • St Gotthard Disease

  • Gotthard Tunnel Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P2260 Tat-beclin 1 99.89% Unkown
HY-P2260B Tat-beclin 1 scrambled 99.10% Unkown
HY-P2260C Tat-beclin 1 scrambled TFA 96.26% Unkown
HY-P2260A Tat-beclin 1 TFA / Unkown
HY-RS05479 GLIPR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19061 Glipr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25551 Glipr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GLIPR2 VGNC VGNC:29405
Macaca mulatta GLIPR2 VGNC VGNC:81414
Canis familiaris GLIPR2 VGNC VGNC:41261
Mus musculus GLIPR2 MGD MGI:1917770
Rattus norvegicus GLIPR2 RGD RGD:1583669
Others GLIPR2 NCBI