HSD17B13/PPAR modulator-1
HSD17B13/PPAR modulator-1 (Compound 17) is a HSD17B13/PPAR multitarget modulator. HSD17B13/PPAR modulator-1 is an inhibitor of HSD17B13, with its IC50 value being 0.91 μM. HSD17B13/PPAR modulator-1 is a PPAR agonist, with the EC50 values for PPARα, PPARδ, and PPARγ being 1.55, 0.12, and 0.01 μM respectively. HSD17B13/PPAR modulator-1 can significantly improve liver function, regulate lipid metabolism, alleviate fibrosis, and exert antioxidant and anti-inflammatory effects in the model of metabolic dysfunction-related steatohepatitis (MASH). HSD17B13/PPAR modulator-1 can be used for the study of MASH.
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- Formel: C31H29F3N2O5S
- Molecular Weight:598.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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PPARα 1.55 μM (EC50) |
PPARδ 0.12 μM (EC50) |
PPARγ 0.01 μM (EC50) |
Chemical Information
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Molecular Weight 598.63
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Formel C31H29F3N2O5S
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SMILES
O=C(C1=C(C)N=C(S1)C2=CC(F)=C(F)C(O)=C2F)N(CC3=CC(C)=C(C(C)=C3)OC(C)(C(O)=O)C)CC4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HSD17B13/PPAR modulator-1 Related Classifications
HY-179015 Related Classifications
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