m-PEG5-triethoxysilane
Based on 1 Customer Validation
m-PEG5-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Reinheit: 95.45%
- CAS. Nr.: 2243566-42-7
- Formel: C21H45NO9Si
- Molecular Weight:483.67
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Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2243566-42-7
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Appearance Liquid
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Molecular Weight 483.67
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Formel C21H45NO9Si
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCOCCC(NCCC[Si](OCC)(OCC)OCC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 25 mg/mL (51.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0675 mL | 10.3376 mL | 20.6753 mL | 51.6881 mL |
| 5 mM | 0.4135 mL | 2.0675 mL | 4.1351 mL | 10.3376 mL | |
| 10 mM | 0.2068 mL | 1.0338 mL | 2.0675 mL | 5.1688 mL | |
| 15 mM | 0.1378 mL | 0.6892 mL | 1.3784 mL | 3.4459 mL | |
| 20 mM | 0.1034 mL | 0.5169 mL | 1.0338 mL | 2.5844 mL | |
| 25 mM | 0.0827 mL | 0.4135 mL | 0.8270 mL | 2.0675 mL | |
| 30 mM | 0.0689 mL | 0.3446 mL | 0.6892 mL | 1.7229 mL | |
| 40 mM | 0.0517 mL | 0.2584 mL | 0.5169 mL | 1.2922 mL | |
| 50 mM | 0.0414 mL | 0.2068 mL | 0.4135 mL | 1.0338 mL |
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