NH2-C16-azide
NH2-C16-azide is a 16-azidohexadecylamine derivative and synthetic intermediate, which can serve as a PROTAC Linker. NH2-C16-azide is applicable to research related to PROTAC synthesis, such as acting as the linker for PROTAC CDK9 degrader-13 (HY-184693).
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- CAS. Nr.: 2755836-98-5
- Formel: C16H34N4
- Molecular Weight:282.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
NH2-C16-azide (compound 8f) serves as a linker for PROTAC CDK9 degrader-13 (HY-184693). PROTAC CDK9 degrader-13 is a selective CDK9 PROTAC degrader. It downregulates the anti-apoptotic protein Mcl-1 and activates the Caspase-3 pathway to induce apoptosis in acute myeloid leukemia cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2755836-98-5
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Molecular Weight 282.47
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Formel C16H34N4
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SMILES
NCCCCCCCCCCCCCCCCN=[N+]=[N-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NH2-C16-azide Related Classifications
HY-184695 Related Classifications
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