Phosphorylase kinase
Based on 1 publication(s) in Google Scholar
Phosphorylase kinase relies on Ca2+ to exert its activity. Phosphorylase kinase’s sensitivity to Ca2+ is influenced by its activation state and pH. Phosphorylase kinase can be activated by adrenaline.
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- CAS. Nr.: 9001-88-1
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Biologische Aktivität
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Publications Citing Use of MedChemExpress (MCE) Phosphorylase kinase
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Biologische Aktivität
Phosphorylase kinase (5 min) increases its affinity for Ca2+ after activation[1].
Phosphorylase kinase is inhibited to uptake Ca2+ through the sarcoplasmic reticulum, and the addition of exogenous Ca2+ can reverse the inhibition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
2.7.1.38
≥ 60 U/mg protein
One unit is defined as the amount of enzyme that will form 1.0 μmolar unit of phosphorylase A from phosphorylase B per min at pH 7.7 at 30°C in the presence of ATP.
Chemical Information
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CAS. Nr. 9001-88-1
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[Phosphorylase kinase]
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Synonyms
PhK
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Reinheit & Dokumentation
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Brostrom CO, et al. The regulation of skeletal muscle phosphorylase kinase by Ca2+. J Biol Chem. 1971 Apr 10;246(7):1961-7. [Content Brief]
[2]. Yeaman SJ, et al. The hormonal control of activity of skeletal muscle phosphorylase kinase. Phosphorylation of the enzyme at two sites in vivo in response to adrenalin. Eur J Biochem. 1975 Feb 3;51(1):93-104. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phosphorylase kinase Related Classifications
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