143 Results for "

GPR1

" in MedChemExpress (MCE) Product Catalog:
Products (143)

143 Results for "GPR1" in MCE Product Catalog:

2
GPR120 Agonist 3
GPR120 Agonist 3
0 Images
2 Cited Publications
Art. -Nr.: HY-101492
CAS. Nr.: 1599477-75-4
Reinheit:  99.51%
Target:  

Free Fatty Acid Receptor

Forschungsgebiete:  

Metabolic Disease

GPR120 Agonist 3 is a selective Gpr120 agonist with a logEC50 of 7.62.
1
SAE-14
SAE-14
0 Images
1 Cited Publications
Art. -Nr.: HY-147222
CAS. Nr.: 1241280-25-0
Reinheit:  98.60%
Synonyms: GPR183 antagonist-1
Target:  

EBI2/GPR183

Forschungsgebiete:  

Neurological Disease Inflammation/Immunology

SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice .
1
NOX-6-18
NOX-6-18
0 Images
1 Cited Publications
Art. -Nr.: HY-157189
CAS. Nr.: 898211-21-7
Reinheit:  99.72%
Synonyms: GPR132 antagonist 1
Target:  

G2A (GPR132)

Forschungsgebiete:  

Metabolic Disease

NOX-6-18 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. NOX-6-18 has promote insulin secretion activity with an EC50 value of 0.7 μM .
1
WLS/GPR177 Antibody (YA7000)
WLS/GPR177 Antibody (YA7000)
0 Images
1 Cited Publications
Art. -Nr.: HY-P87317
Synonyms: C1orf139 antibody; DKFZp686I0788 antibody; Evenness interrupted, Drosophila, homolg of antibody; EVI antibody; FLJ23091 antibody; G protein coupled receptor 177 antibody; GPR 177 antibody; Integral membrane protein GPR177 antibody; MGC131760 antibody; MGC14878 antibody

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

GPR109 receptor agonist-1
GPR109 receptor agonist-1
0 Images
Art. -Nr.: HY-107580
CAS. Nr.: 306935-41-1
Reinheit:  99.91%
Target:  

GPR109A

Forschungsgebiete:  

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

GPR109 receptor agonist-1 is a highly selective agonist of the human orphan G protein-coupled receptor GPR109b, and does not activate the mouse homologous receptor PUMA-G. GPR109 receptor agonist-1 functionally modulates the human GPR109b receptor via the cAMP signaling pathway, with an EC50 of 400 nM. GPR109 receptor agonist-1 inhibits isoproterenol (HY-B0468)-stimulated lipolysis in human subcutaneous adipocytes, with efficacy comparable to that of Niacin (HY-B0143), and does not act on β-adrenergic receptors. GPR109 receptor agonist-1 can be used in studies related to dyslipidemia and atherosclerosis .
GPR110 peptide agonist P12 acetate
GPR110 peptide agonist P12 acetate
0 Images
Art. -Nr.: HY-P10495A
Target:  

Peptides

Forschungsgebiete:  

Cancer

GPR110 peptide agonist P12 acetate is the acetate salt form of GPR110 peptide agonist P12 (HY-P10495). GPR110 peptide agonist P12 acetateis a peptide that acts as a GPR110 agonist. GPR110 peptide agonist P12 acetate can significantly enhance the initial rate of GPR110 stimulated G protein GTPγS binding. GPR110 peptide agonist P12 acetate mimics the action of natural ligands, causing the extracellular domain (ECD) of the GPR110 to dissociate from the seven transmembrane domains (7TM), exposing the β-strand-13/stalk region at the N-terminus of the 7TM domain, which acts as an agonist to activate G protein signaling. GPR110 peptide agonist P12 acetate can be used in the study of developmental disorders and cancers related to GPR110 .
GPR15 antagonist-1
GPR15 antagonist-1
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Art. -Nr.: HY-177116
CAS. Nr.: 252280-67-4
Target:  

HIV

Forschungsgebiete:  

Infection Inflammation/Immunology

GPR15 antagonist-1 (Compound 5) is a GPR15 antagonist. G protein-coupled receptor 15 (GPR15) is an extensively studied GPCRs involving HIV infection, colonic inflammation, and smoking-related diseases .
GPR17 antagonist 1
GPR17 antagonist 1
0 Images
Art. -Nr.: HY-170589
CAS. Nr.: 1574405-61-0
Target:  

Transmembrane Glycoprotein

Forschungsgebiete:  

Neurological Disease

GPR17 antagonist 1 (compound 978) is a GPR17 antagonist. GPR17 antagonist 1 can be used in the study of diabetes and obesity .
GPR183 antagonist-3
GPR183 antagonist-3
0 Images
Art. -Nr.: HY-157939
CAS. Nr.: 3054870-33-3
Target:  

EBI2/GPR183

Forschungsgebiete:  

Inflammation/Immunology

GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis .
GPR139 agonist-2
GPR139 agonist-2
0 Images
Art. -Nr.: HY-149651
CAS. Nr.: 2983118-29-0
Reinheit:  99.80%
Target:  

GPR139

Forschungsgebiete:  

Neurological Disease

GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research .
GPR120 modulator 1
GPR120 modulator 1
0 Images
Art. -Nr.: HY-50162
CAS. Nr.: 1050506-75-6
Target:  

Free Fatty Acid Receptor

Forschungsgebiete:  

Metabolic Disease

GPR120 modulator 1 is a G protein coupled receptor 120 (GPR120) modulator extracted from patent US8394841B2, compound example F1. GPR120 modulator 1 can be used for the research of diseases associated with abnormal or deregulated GPR120, such as diabetes .
GPR120 modulator 2
GPR120 modulator 2
0 Images
Art. -Nr.: HY-50172
CAS. Nr.: 1050506-87-0
Target:  

Free Fatty Acid Receptor

Forschungsgebiete:  

Metabolic Disease

GPR120 modulator 2 is a G protein coupled receptor 120 (GPR120) modulator extracted from patent US8394841B2, compound example F13. GPR120 modulator 2 can be used for the research of diseases associated with abnormal or deregulated GPR120, such as diabetes .
GPR183 inverse agonist-1
GPR183 inverse agonist-1
0 Images
Art. -Nr.: HY-175306
CAS. Nr.: 2380033-51-0
Target:  

EBI2/GPR183 Arrestin

Forschungsgebiete:  

Inflammation/Immunology Cancer

GPR183 inverse agonist-1 (Compound 78) is a GPR183 inverse agonist. GPR183 inverse agonist-1 inhibits the GPR183-mediated Gi activation and β-arrestin2 recruitment, and blocks PBMC migration. GPR183 inverse agonist-1 can be used for inflammatory, autoimmune and neoplastic disorders research .
GPR110 peptide agonist P12
GPR110 peptide agonist P12
0 Images
Art. -Nr.: HY-P10495
CAS. Nr.: 1778685-49-6
Target:  

Transmembrane Glycoprotein

Forschungsgebiete:  

Others Cancer

GPR110 peptide agonist P12 is a peptide that acts as a GPR110 agonist. GPR110 peptide agonist P12 can significantly enhance the initial rate of GPR110 stimulated G protein GTPγS binding. GPR110 peptide agonist P12 mimics the action of natural ligands, causing the extracellular domain (ECD) of the GPR110 to dissociate from the seven transmembrane domains (7TM), exposing the β-strand-13/stalk region at the N-terminus of the 7TM domain, which acts as an agonist to activate G protein signaling. GPR110 peptide agonist P12 can be used in the study of developmental disorders and cancers related to GPR110 .
Gpr119 Mouse Pre-designed siRNA Set A
Gpr119 Mouse Pre-designed siRNA Set A
Art. -Nr.: HY-RS05653
Target:  

Small Interfering RNA (siRNA)

Forschungsgebiete:  

Others

Gpr119 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr119 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

GPR17 modulator-1
GPR17 modulator-1
0 Images
Art. -Nr.: HY-164311
CAS. Nr.: 3039853-91-0
Target:  

Transmembrane Glycoprotein

Forschungsgebiete:  

Neurological Disease

GPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17, with an IC50<10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable .
GPR10 agonist 1
GPR10 agonist 1
0 Images
Art. -Nr.: HY-P10378
Target:  

GnRH Receptor

Forschungsgebiete:  

Metabolic Disease

GPR10 agonist 1 (compound 18-S4) is a potent GPR10 agonist with EC50 values of 80, 7.8 nM in the presence (10%) or absence (0%) of FBS, respectively. GPR10 agonist 1 has the potential for the research of chronic obesity .
GPR109 receptor agonist-3
GPR109 receptor agonist-3
0 Images
Art. -Nr.: HY-176817
CAS. Nr.: 944559-31-3
Target:  

GPR109A

Forschungsgebiete:  

Cardiovascular Disease Metabolic Disease

GPR109 receptor agonist-3 is an orally active GPR109 receptor agonist, with an IC50 of 310 nM. GPR109 receptor agonist-3 retains the antioxidation and cytoprotection of Lipoic acid (HY-18733). GPR109 receptor agonist-3 reduces total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and increases high-density lipoprotein cholesterol (HDL-C) in high-fat diet-fed rats. GPR109 receptor agonist-3 can be used for the study of atherosclerosis .
Gpr18 Mouse Pre-designed siRNA Set A
Gpr18 Mouse Pre-designed siRNA Set A
Art. -Nr.: HY-RS17979
Target:  

Small Interfering RNA (siRNA)

Forschungsgebiete:  

Others

Gpr18 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr18 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gpr132 Mouse Pre-designed siRNA Set A
Gpr132 Mouse Pre-designed siRNA Set A
Art. -Nr.: HY-RS17514
Target:  

Small Interfering RNA (siRNA)

Forschungsgebiete:  

Others

Gpr132 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr132 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Assay Types