3054870-33-3
3054870-33-3
Chemical Structure
GPR183 antagonist-3
- CAS No.: 3054870-33-3
- Formula:C21H19BrN4O2S
- Molecular Weight:471.37
InChIKey: YVICAZJLKUSZMU-FPYGCLRLSA-N
SMILES: BrC1=CC=C(C=C1)/C=C/C(N2CCN(CC2)C(C3=CC=C4N=C(SC4=C3)N)=O)=O
Biological Activity: GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis[1].
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GPR183 antagonist-3 | 98.79% | GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis. | ||||||||||||||||||||
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References
Keywords
