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Art. -Nr.: HY-184545

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STING ligand-5

STING ligand-5 (Compound 4) is a ligand for target protein of PROTAC, which is applicable to the synthesis of PROTAC UNC9036 (HY-158048).

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CAS. Nr.: 3055995-98-4
Formel: C₄₂H₅₀N₁₂O₈
Molecular Weight:850.92

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

STING ligand-5 Chemical Structure

CAS. Nr.: 3055995-98-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

STING ligand-5 (Compound 4) is a ligand for target protein of PROTAC, which is applicable to the synthesis of PROTAC UNC9036 (HY-158048)^[1].

In Vitro

Ligands of the target protein cause PROTAC to bind to the target protein, leading to ubiquitination and subsequent degradation of the protein.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3055995-98-4
Molecular Weight 850.92
Formel C₄₂H₅₀N₁₂O₈
SMILES

O=C(O)C1=CC2=C(C(OC)=C1)N(C/C=C/CN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=C3C(OCCCN6CCOCC6)=CC(C(N)=O)=C5)C(NC(C7=CC(C)=NN7CC)=O)=N2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Zhu Z, et al.. Development of VHL-recruiting STING PROTACs that suppress innate immunity. Cellular and molecular life sciences : CMLS. 2023 May 14;80(6):149. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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