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Tozorakimab

(Synonyms: MEDI-3506)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease.

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  • Reinheit: 98.82%
  • CAS. Nr.: 2376858-66-9
  • Molecular Weight:144.66 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tozorakimab
  • Experimental Validation Results for Tozorakimab
  • Experimental Validation Results for Tozorakimab
  • Tozorakimab Chemical Structure
    Tozorakimab Chemical Structure
CAS. Nr.: 2376858-66-9
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[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG1 lambda

  • 1/16

    Immobilized Human IL-33 Protein can bind Tozorakimab. The EC50 for this effect is 3.21 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 HUVEC cells with Tozorakimab (HY-P99550, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 lambda2 Isotype Control (HY-P990096, blue) was used as the isotype control.

  • Tozorakimab Chemical Structure
    1/16
  • Tozorakimab
  • Immobilized Human IL-33 Protein can bind Tozorakimab. The EC50 for this effect is 3.21 ng/mL.
  • Flow cytometric analysis of 1.5×106 HUVEC cells with Tozorakimab (HY-P99550, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 lambda2 Isotype Control (HY-P990096, blue) was used as the isotype control.