Urease-IN-3
Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC50 of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound.
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- CAS. Nr.: 2543651-72-3
- Formel: C23H15FN2O4
- Molecular Weight:402.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 2543651-72-3
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Molecular Weight 402.37
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Formel C23H15FN2O4
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SMILES
O=C(N/N=C/C1=C(O)C=CC2=C1OC(C3=CC=C(F)C=C3)=CC2=O)C4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (248.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
Verweise
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4853 mL | 12.4264 mL | 24.8527 mL | 62.1319 mL |
| 5 mM | 0.4971 mL | 2.4853 mL | 4.9705 mL | 12.4264 mL | |
| 10 mM | 0.2485 mL | 1.2426 mL | 2.4853 mL | 6.2132 mL | |
| 15 mM | 0.1657 mL | 0.8284 mL | 1.6568 mL | 4.1421 mL | |
| 20 mM | 0.1243 mL | 0.6213 mL | 1.2426 mL | 3.1066 mL | |
| 25 mM | 0.0994 mL | 0.4971 mL | 0.9941 mL | 2.4853 mL | |
| 30 mM | 0.0828 mL | 0.4142 mL | 0.8284 mL | 2.0711 mL | |
| 40 mM | 0.0621 mL | 0.3107 mL | 0.6213 mL | 1.5533 mL | |
| 50 mM | 0.0497 mL | 0.2485 mL | 0.4971 mL | 1.2426 mL | |
| 60 mM | 0.0414 mL | 0.2071 mL | 0.4142 mL | 1.0355 mL | |
| 80 mM | 0.0311 mL | 0.1553 mL | 0.3107 mL | 0.7766 mL | |
| 100 mM | 0.0249 mL | 0.1243 mL | 0.2485 mL | 0.6213 mL |
Urease-IN-3 Related Classifications
HY-147787 Related Classifications
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