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Cat. No.: HY-N11721

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5-Hydroxyaloin A

5-Hydroxyaloin A is a polyphenolic antioxidant agent. 5-Hydroxyaloin A forms hydrogen bonding interactions at lipase’s active site and SOD’s active site with low binding energy. 5-Hydroxyaloin A inhibits microsomal lipid peroxidation induced by ferrous-cysteine, reducing malondialdehyde production. 5-Hydroxyaloin A can be used for the research of obesity.

For research use only. We do not sell to patients.

CAS No.: 138373-23-6
Formula: C₂₁H₂₂O₁₀
Molecular Weight:434.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

5-Hydroxyaloin A Chemical Structure

CAS No.: 138373-23-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

5-Hydroxyaloin A shows strong molecular binding affinity for porcine pancreatic lipase, with a free binding energy of -16.08 kcal/mol^[1].
5-Hydroxyaloin A shows strong molecular binding affinity for superoxide dismutase, with a free binding energy of -12.97 kcal/mol^[1].
5-Hydroxyaloin A binds to α-glucosidase with a free binding energy of -12.94 kcal/mol^[1].
5-Hydroxyaloin A binds to porcine pancreatic α-amylase with a free binding energy of -12.13 kcal/mol^[1].
5-Hydroxyaloin A binds to catalase with a free binding energy of -16.12 kcal/mol^[1].
5-Hydroxyaloin A (10 μM) inhibits ferrous-cysteine-induced microsomal lipid peroxidation with an inhibitory rate of 31.0%^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 138373-23-6
Molecular Weight 434.39
Formula C₂₁H₂₂O₁₀
SMILES

OC1=C2[C@@]([C@]3([H])O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)([H])C4=CC(CO)=CC(O)=C4C(C2=C(C=C1)O)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huda Ismail, et al. Aloe ferox leaf gel extracts attenuate redox imbalance in oxidative renal injury and stimulates glucose uptake, whilst inhibiting key enzymes linked to diabetes and obesity. Scientific African. Volume 26, December 2024, e02425.

[2]. Lv L, et al. Three new antioxidant C-glucosylanthrones from Aloe nobilis. J Asian Nat Prod Res. 2010 Jun;12(6):443-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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