138373-23-6
Chemical Structure
5-Hydroxyaloin A
- CAS No.: 138373-23-6
- Formula:C21H22O10
- Molecular Weight:434.39
IUPAC Name: (R)-1,5,8-trihydroxy-3-(hydroxymethyl)-10-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)anthracen-9(10H)-one
InChIKey: LJCDCYLYUCZUGL-UQBALUMJSA-N
SMILES: OC1=C2[C@@]([C@]3([H])O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)([H])C4=CC(CO)=CC(O)=C4C(C2=C(C=C1)O)=O
Biological Activity: 5-Hydroxyaloin A is a polyphenolic antioxidant agent. 5-Hydroxyaloin A forms hydrogen bonding interactions at lipase’s active site and SOD’s active site with low binding energy. 5-Hydroxyaloin A inhibits microsomal lipid peroxidation induced by ferrous-cysteine, reducing malondialdehyde production. 5-Hydroxyaloin A can be used for the research of obesity[1][2].
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5-Hydroxyaloin A | 5-Hydroxyaloin A is a polyphenolic antioxidant agent. 5-Hydroxyaloin A forms hydrogen bonding interactions at lipase’s active site and SOD’s active site with low binding energy. 5-Hydroxyaloin A inhibits microsomal lipid peroxidation induced by ferrous-cysteine, reducing malondialdehyde production. 5-Hydroxyaloin A can be used for the research of obesity. | |||||||||||||||||||||
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References
- [1]. Huda Ismail, et al. Aloe ferox leaf gel extracts attenuate redox imbalance in oxidative renal injury and stimulates glucose uptake, whilst inhibiting key enzymes linked to diabetes and obesity. Scientific African. Volume 26, December 2024, e02425.
- [2]. Lv L, et al. Three new antioxidant C-glucosylanthrones from Aloe nobilis. J Asian Nat Prod Res. 2010 Jun;12(6):443-7. [Content Brief]
