Mov10 - Mov10 RISC complex RNA helicase Gene

Also Known as Mov-10

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17454

Summary

Predicted to enable 5'-3' RNA helicase activity and RNA binding activity. Involved in negative regulation of transposition, RNA-mediated and regulation of neuron projection arborization. Located in cytosol and nucleus. Is expressed in brain; gut; sensory organ; testis; and turbinate bone primordium. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RISC complex RNA helicase). [provided by Alliance of Genome Resources, Apr 2022]

Mov10 Products (7)

mRNA Protein Name
NM_001163440.2 NP_001156912.2 putative helicase MOV-10 isoform b
NM_001163441.2 NP_001156913.1 putative helicase MOV-10 isoform b
NM_001410425.1 NP_001397354.1 putative helicase MOV-10 isoform c
NM_001410426.1 NP_001397355.1 putative helicase MOV-10 isoform c
NM_001410427.1 NP_001397356.1 putative helicase MOV-10 isoform c
NM_001410428.1 NP_001397357.1 putative helicase MOV-10 isoform c
NM_008619.3 NP_032645.2 putative helicase MOV-10 isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25464849 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of neuron projection arborization IMP
IMP: Inferred from mutant phenotype
28662698 MGI
involved in retrotransposon silencing IMP
IMP: Inferred from mutant phenotype
28662698 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
28662698 MGI
located in nucleus IDA
IDA: Inferred from direct assay
28662698 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative helicase MOV-10

  • moloney leukemia virus 10 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08603 MOV10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08604 MOV10L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22648 Mov10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29162 Mov10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mov10 NCBI NCBI:4343