Dropropizine-d4
Dropropizine-d4 ((±)-Dropropizine-d4) is deuterium labeled Dropropizine. Dropropizine ((±)-Dropropizine) belongs to the phenylpiperazine group of organic compounds. Dropropizine is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
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- CAS No.: 2514953-45-6
- Formule: C13H16D4N2O2
- Masse moléculaire:240.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2514953-45-6
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Unlabeled Cas 17692-31-8
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Masse moléculaire 240.33
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Formule C13H16D4N2O2
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SMILES
OCC(CN1C([2H])([2H])CN(CC1([2H])[2H])C2=CC=CC=C2)O
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Synonyms
(±)-Dropropizine-d4; UCB-196-d4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Machado AKMS, et, al. Characteristics, Properties and Analytical Methods for Determination of Dropropizine and Levodropropizine: A Review. Crit Rev Anal Chem. 2019 Dec 9;1-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)