DSG Crosslinker
Based on 5 publication(s) in Google Scholar
DSG Crosslinker is an amine-reactive and noncleavable protein crosslinker. DSG Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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- Pureté: 98.0%
- CAS No.: 79642-50-5
- Formule: C13H14N2O8
- Masse moléculaire:326.26
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DSG Crosslinker
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Customer Validation & Images
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WB
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WB
Activité biologique
Chemical Information
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CAS No. 79642-50-5
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Appearance Solid
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Masse moléculaire 326.26
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Formule C13H14N2O8
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Color Off-white to gray
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SMILES
O=C(CCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O
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Synonyms
Disuccinimidyl glutarate
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (5)
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Journal Impact Factor
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Most Recent
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Nat Commun
2026 Feb 20;17(1):2963. PMID: 41720774 -
Adv Sci (Weinh)
Dimer-Specific FokT-seq Reveals DNA-Binding Dimerization and Novel Genomic Targets of TDP-43. [Abstract]2025 Aug 23:e08902. PMID: 40847753
DSG Crosslinker purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 23:e08902. [Abstract]
DSG Crosslinker (0-400 μM; 10 min). Crosslinking of 3×FLAG‐TDP‐43 in 293T cells with increasing concentrations of DSG shows an increase in the dimeric form and a decrease in the monomeric form. GAPDH was used as the loading control.
DSG Crosslinker purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 23:e08902. [Abstract]
DSG Crosslinker (100 μM; 10 min). Overexpression of 3×FLAG‐TDP‐43, 3×FLAG‐NLS‐FokI, 3×FLAG‐NLS‐FokT, and 3×FLAG‐NLS‐FokTN6A plasmids in 293T cells followed by crosslinking with 100 µM DSG. Western blot analysis was performed to examine their dimerization.
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Genome Biol
DNA G-quadruplex profiling in skeletal muscle stem cells reveals functional and mechanistic insights. [Abstract]2025 Sep 5;26(1):269. PMID: 40913227 -
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Solvant et solubilité
DMSO : 100 mg/mL (306.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (247 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.0650 mL | 15.3252 mL | 30.6504 mL | 76.6260 mL |
| 5 mM | 0.6130 mL | 3.0650 mL | 6.1301 mL | 15.3252 mL | |
| 10 mM | 0.3065 mL | 1.5325 mL | 3.0650 mL | 7.6626 mL | |
| 15 mM | 0.2043 mL | 1.0217 mL | 2.0434 mL | 5.1084 mL | |
| 20 mM | 0.1533 mL | 0.7663 mL | 1.5325 mL | 3.8313 mL | |
| 25 mM | 0.1226 mL | 0.6130 mL | 1.2260 mL | 3.0650 mL | |
| 30 mM | 0.1022 mL | 0.5108 mL | 1.0217 mL | 2.5542 mL | |
| 40 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 50 mM | 0.0613 mL | 0.3065 mL | 0.6130 mL | 1.5325 mL | |
| 60 mM | 0.0511 mL | 0.2554 mL | 0.5108 mL | 1.2771 mL | |
| 80 mM | 0.0383 mL | 0.1916 mL | 0.3831 mL | 0.9578 mL | |
| 100 mM | 0.0307 mL | 0.1533 mL | 0.3065 mL | 0.7663 mL |
DSG Crosslinker Related Classifications
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