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Cat. No.: HY-123478

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Fengabine

(Synonyms: SL 79229)

Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 80018-06-0
Formule: C₁₇H₁₇Cl₂NO
Masse moléculaire:322.23

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Fengabine Chemical Structure

CAS No.: 80018-06-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression^[1].

In Vivo

Fengabine (50 mg/kg; i.p.; 2 days) prevents completely the learned helplessness induced by the unavoidable shock^[1].
Fengabine (150 mg/kg; i.p) decreases the percentage of time spent. Fengabine (25~50 mg/kg; i.p.) reverses the deficit in learning the step-down avoidance task^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rats^[1]
Dosage:

50 mg/kg
Administration:

I.p.
Result:

Prevented completely the learned helplessness induced by the unavoidable shock.

Chemical Information

CAS No. 80018-06-0
Masse moléculaire 322.23
Formule C₁₇H₁₇Cl₂NO
SMILES

OC1=CC=C(C=C1/C(C2=CC=CC=C2Cl)=N\CCCC)Cl
Synonyms

SL 79229
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ascalone V, et al. Determination of the GABAergic antidepressant drug fengabine and some of its metabolites in plasma by capillary gas chromatography with electron-capture detection. J Chromatogr. 1989;490(1):81-90. [Content Brief]

[2]. Lloyd KG, et al. Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. J Pharmacol Exp Ther. 1987;241(1):245-250. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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