NR2F6 - nuclear receptor subfamily 2 group F member 6 Gene

Also Known as EAR2; EAR-2; ERBAL2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2063

About NR2F6

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:17,231,883-17,245,919 (from NCBI)

This gene has 2 transcripts (splice variants), 285 orthologues and 11 paralogues. Broad expression in colon (RPKM 27.8), stomach (RPKM 20.8) and 23 other tissues.

Summary

Enables DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NR2F6 Products (1)

mRNA Protein Name
NM_005234.4 NP_005225.2 nuclear receptor subfamily 2 group F member 6

NR2F6 Protein Structure

zf-C4

zf-C4: Zinc finger, C4 type (two domains) (55 - 123)

Hormone_recep

Hormone_recep: Ligand-binding domain of nuclear hormone receptor (198 - 376)

  • 0
  • 100
  • 200
  • 300
  • 404 a.a.
Protein Preferred Names Protein Names

nuclear receptor subfamily 2 group F member 6

  • ERBA-related gene-2

NR2F6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
NR2F6 P10588 NR2F2 Homo sapiens P24468
Anti Tag CoIP
33961781
Intra
NR2F6 P10588 NAP1L1 Homo sapiens P55209
Display Tech
20195357
Cross: Cross-species interaction Intra: Intraspecies interaction

NR2F6 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P810872 NR2F6 Antibody WB, IHC-P, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Sebaceous Adenocarcinoma

  • Sebaceous Carcinoma

  • Adenocarcinoma Of The Sebaceous Gland

  • Malignant Neoplasm Of Sebaceous Gland

  • Malignant Sebaceous Tumor

  • Adenocarcinoma, Sebaceous

  • Malignant Sebaceous Neoplasm

  • Sebaceous Gland Neoplasms
46,Xy Sex Reversal

  • Swyer Syndrome

  • Pure Gonadal Dysgenesis 46,Xy

  • Gonadal Dysgenesis, Xy Female Type

  • Gonadal Dysgenesis, 46,Xy

  • 46,Xy Cgd

  • 46,Xy Complete Gonadal Dysgenesis

  • 46,Xy Pure Gonadal Dysgenesis

  • 46 Xy Gonadal Dysgenesis

  • 46, Xy Cgd

  • 46, Xy Complete Gonadal Dysgenesis

  • 46, Xy Pure Gonadal Dysgenesis

  • Xy Pure Gonadal Dysgenesis

  • Female With 46,Xy Karyotype

  • Xy Females
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-147228 NR2F6 modulator-1 Modulator 99.46% Unkown
HY-W649594 NR2F6 modulator-2 Modulator 99.46% Unkown
HY-RS09543 NR2F6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118912 BMH-9 / Unkown
HY-RS17508 Nr2f6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23965 Nr2f6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NR2F6 MGD MGI:1352453
Felis catus NR2F6 VGNC VGNC:68552
Macaca mulatta NR2F6 VGNC VGNC:75514
Rattus norvegicus NR2F6 RGD RGD:621685
Canis familiaris NR2F6 VGNC VGNC:43951
Bos taurus NR2F6 VGNC VGNC:32242
Others NR2F6 NCBI