Fh - fumarate hydratase Gene

Also Known as Fh1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24368

Summary

Enables fumarate hydratase activity. Involved in fumarate metabolic process; malate metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Human ortholog(s) of this gene implicated in fumarase deficiency and lung non-small cell carcinoma. Orthologous to human FH (fumarate hydratase). [provided by Alliance of Genome Resources, Apr 2022]

Fh Products (1)

mRNA Protein Name
NM_017005.2 NP_058701.2 fumarate hydratase, mitochondrial precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables fumarate hydratase activity IMP
IMP: Inferred from mutant phenotype
2914923 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fumarate hydratase, mitochondrial

  • fumarase

  • fumarate hydratase 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit Effect
Pureté Phase
HY-34350 2-(Aminomethyl)phenol Inhibitor 99.45% Phase 2
HY-N0842 Bevirimat Inhibitor 99.82% Phase 2
HY-12346 FH1 Inhibitor 99.17% Phase 1
Inhibitory Antibodies (1)
Cat. No. Nom du produit Effect
Pureté Phase
HY-P991067 Vensobafusp alfa Inhibitor 97% Phase 2

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-15721 FH535 Inhibitor 99.95% Unkown
HY-144896 FHT-1015 Inhibitor 98.41% Unkown
HY-D0917 NIR-Red Dead Cell-1 Dye ≥96.0% Unkown
HY-150686 Chitin synthase inhibitor 4 Inhibitor 98.97% Unkown
HY-RS07575 LDLR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-160875 GST-FH.1 Inhibitor 90.0% Unkown
HY-E70062 α-2,3-Sialyltransferase, pasteurella multocida / Unkown
HY-W028210 O-Phthalimide-C5-acid 98.0% Unkown
HY-N8378 Clonostachydiol / Unkown
HY-P2969 Complement factor I 93.00% Unkown
HY-RS02561 CFH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04930 FH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-160874 GST-FH.4 Inhibitor 90.0% Unkown
HY-N9220 6-Epi-albassitriol Inhibitor / Unkown
HY-RS17117 fh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23562 Fh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23978 Cfh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P990955 Ebribafusp alfa Inhibitor 96.40% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fh NCBI NCBI:2271