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Cat. No.: HY-118279

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KSCM-1

KSCM-1 is a selective sigma-1 receptor ligand with a K_i of 27.5 nM. KSCM-1 shows more selective for sigma-1 over sigma-2, and shows no significant affinity at non-sigma receptors.

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CAS No.: 1415247-17-4
Formule: C₂₆H₃₂N₂O₄
Masse moléculaire:436.54

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

KSCM-1 Chemical Structure

CAS No.: 1415247-17-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Description

KSCM-1 is a selective sigma-1 receptor ligand with a K_i of 27.5 nM. KSCM-1 shows more selective for sigma-1 over sigma-2, and shows no significant affinity at non-sigma receptors^[1].

IC₅₀ & Target^[1]

Sigma 1 Receptor

27.5 nM (Ki)

Sigma 2 Receptor

528 nM (Ki)

Voir tous les produits spécifiques à Isoform Sigma Receptor :

Chemical Information

CAS No. 1415247-17-4
Masse moléculaire 436.54
Formule C₂₆H₃₂N₂O₄
SMILES

O=C(N(CCCN1CCCCC1)C2=CC=CC=C2)C3=C(C4=CC(OC)=C(C=C4O3)OC)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Karla-Sue C Marriott, et al. Synthesis of N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamides as new selective ligands for sigma receptors. Bioorg Med Chem. 2012 Dec 1;20(23):6856-61. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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KSCM-1

Voir tous les produits spécifiques à Isoform Sigma Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

KSCM-1 Related Classifications

HY-118279 Related Classifications