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Cat. No.: HY-106495

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Vadocaine

(Synonyms: OR K-242)

Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain.

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CAS No.: 72005-58-4
Formule: C₁₈H₂₈N₂O₂
Masse moléculaire:304.43

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Vadocaine Chemical Structure

CAS No.: 72005-58-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain^[1].

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In Vivo

In guinea-pigs, Vadocaine (2.5 mg/kg; p.o.) reduces by about 70% the cough episodes induced by sulphur dioxide or ammonia^[1].
In cats, Vadocaine (3 mg/kg; i.v.) inhibits by about 80% for 10 min the cough reflex initiated by mechanical irritation of the trachea^[1].
Vadocaine causes local anaesthesia in the guinea-pig wheal preparation at concentrations of 0.25% and 0.5%, and on the guinea-pig cornea at 0.5%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 72005-58-4
Masse moléculaire 304.43
Formule C₁₈H₂₈N₂O₂
SMILES

CC(CCCC1)N1CCC(NC2=C(C=C(C)C=C2C)OC)=O
Synonyms

OR K-242
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. P T Männistö, et al. Antitussive action of the new anilide derivative vadocaine hydrochloride compared with codeine phosphate in four animal models. Arzneimittelforschung. 1988 Apr;38(4A):598-604. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Vadocaine

Voir tous les produits spécifiques à Isoform Adrenergic Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Vadocaine Related Classifications

HY-106495 Related Classifications