c-Kit-IN-12
C-Kit-IN-12 (Compound 2a) is a potent c-Kit inhibitor, with its IC50 value for c-Kit being less than 10 nM in four KIT mutant cell models (BAF3 KIT EX11 DEL, EX11 DEL/D816H, EX11 DEL/T670I, EX11 DEL/V654A). C-Kit-IN-12 can be used for studying diseases or disorders related to c-Kit, such as cancer.
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- CAS. Nr.: 2797973-68-1
- Formel: C24H20F3N5O3S
- Molecular Weight:515.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 2797973-68-1
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Molecular Weight 515.51
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Formel C24H20F3N5O3S
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SMILES
C(NC1=CC(C#CC=2SC(NC(=O)N3C[C@H](O)CC3)=NC2)=C(C)C=C1)(=O)C4=CC(C(F)(F)F)=CC=N4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)