Hancockiamide D
Hancockiamide D is a phenylpropanoid piperazine alkaloid found in the Australian soil fungus Aspergillus hancockii. Hancockiamide D induces cytotoxic activity in cancer cells and shows no activity in fibroblasts. Hancockiamide D can be used for the research of murine myeloma.
For research use only. We do not sell to patients.
- CAS No.: 2758265-37-9
- Formula: C20H26N2O3
- Molecular Weight:342.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Hancockiamide D (compound 4) undergoes N-trans-cinnamoylation catalyzed by the single-module nonribosomal peptide synthetase Hkm11 in vitro to produce Hancockiamide A; the cytochrome P450 Hkm5 converts a portion of Hancockiamide D into H[1].
Hancockiamide D exhibits potent cytotoxic activity against mouse myeloma NS-1 cells (MIC = 3.1 μg/mL), while showing no activity against neonatal foreskin fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2758265-37-9
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Molecular Weight 342.44
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Formula C20H26N2O3
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SMILES
C(C1=CC(OC)=C(O)C(OC)=C1)[C@H]2CN[C@@H](CC3=CC=CC=C3)CN2
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Structure Classification
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Initial Source
Aspergillus hancockii
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hancockiamide D Related Classifications
HY-N19181 Related Classifications
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