(S)-MDL-101146
(S)-MDL-101146 is the S-isomer of MDL-101146. MDL-101146 is an orally active, competitive and reversible inhibitor against human neutrophil elastase (HNE) with a Ki value of 25 nM. MDL-101146 inhibits HNE-induced hemorrhage in hamsters. MDL-101146 is promising for research of emphysema, rheumatoid arthritis, chronic bronchitis, cystic fibrosis, adult respiratory distress syndrome and glomerulonephritis.
For research use only. We do not sell to patients.
- CAS No.: 163660-59-1
- Formula: C29H37F5N4O6
- Molecular Weight:632.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 163660-59-1
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Molecular Weight 632.62
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Formula C29H37F5N4O6
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SMILES
O=C(NC([C@H](C(C)C)NC(C1=CC=C(C(N2CCOCC2)=O)C=C1)=O)=O)[C@H]3N([C@@H](C(C)C)C(C(F)(F)C(F)(F)F)=O)CCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-MDL-101146 Related Classifications
HY-120039A Related Classifications
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