Dimethyldithiocarbamate-d6 sodium dihydrate
Dimethyldithiocarbamate-d6 sodium dihydrate is the deuterium-labeled Dimethyldithiocarbamate (HY-W098697). Ferric dimethyl‐dithiocarbamate (ferbam) exhibits oral toxicity in rodents.
For research use only. We do not sell to patients.
- Formula: C3H4D6NNaO2S2
- Molecular Weight:185.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen,carbon,and other elements have been incorporated into drug molecules,largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 185.27
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Formula C3H4D6NNaO2S2
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SMILES
S=C(S[Na])N(C([2H])([2H])[2H])C([2H])([2H])[2H].O.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Lee CC, et al. Oral toxicity of ferric dimethyl-dithiocarbamate (ferbam) and tetramethylthiuram disulfide (thiram) in rodents. J Toxicol Environ Health. 1978 Jan;4(1):93-106. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)