FLT3-IN-31
FLT3-IN-31 (compound 10q) is a potent FLT3 inhibitor with IC50 values of 0.16, 2.4 nM for FLT3, FLT3-D835Y, resprctively. FLT3-IN-31 shows antiproliferation activity. FLT3-IN-31 decreases the protein expression of p-FLT3, P-STAT5, P-ERK. FLT3-IN-31 induces apoptosis and cell cycle arrest at G1 phase. FLT3-IN-31 shows antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2290545-53-6
- Formula: C25H24FN5O
- Molecular Weight:429.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2290545-53-6
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Molecular Weight 429.49
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Formula C25H24FN5O
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SMILES
NC1=NC=CC(C2=CC=C3C(NN=C3/C=C/C4=CC=C(C(F)=C4)CN5CCOCC5)=C2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FLT3-IN-31 Related Classifications
HY-174137 Related Classifications
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