mPGES1-IN-8
mPGES1-IN-8, is a novel microsomal prostaglandin E synthase 1 (mPGES1) inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 1381846-21-4
- Formula: C16H19ClN4O2
- Molecular Weight:334.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.87 μM
Compound: 26
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Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta by EIA method
Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta by EIA method
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[PMID: 26653180] |
Chemical Information
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CAS No. 1381846-21-4
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Molecular Weight 334.80
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Formula C16H19ClN4O2
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SMILES
O=C(NC1=NC=CN1)C2=CC(CNC(C(C)(C)C)=O)=CC=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mPGES1-IN-8 Related Classifications
HY-13475 Related Classifications
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