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Products are for research use only. Not for human use. We do not sell to patients.
hPGDS-IN-1 Chemical Structure
|Product name: hPGDS-IN-1|
|Cat. No.: HY-12791|
hPGDS-IN-1 is a hPGDS inhibitor ,with IC50 of 12 nM in the Fluorescence Polarization Assay or the EIA assay.
IC50 value: 12 nM
The detailed information please refer to WO2011044307A1 and WO2010080563A2
|M.Wt||416.43||Storage||Please store the product under the recommended conditions in the Certificate of Analysis.|
|Solvent & Solubility||
DMSO: ≥ 30 mg/mL
|1 mg||5 mg||10 mg|
|1 mM||2.4014 mL||12.0068 mL||24.0136 mL|
|5 mM||0.4803 mL||2.4014 mL||4.8027 mL|
|10 mM||0.2401 mL||1.2007 mL||2.4014 mL|
. Vandeusen, Christopher L, et al. Phenyloxadiazole derivatives as PGD inhibitors and their preparation, pharmaceutical compositions and use in the treatment of allergic and inflammatory disorders. From PCT Int. Appl. (2011), WO 2011044307 A1 20110414.
. Weiberth Franz J, et al. Demonstration on Pilot-Plant Scale of the Utility of 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) as a Catalyst in the Efficient Amidation of an Unactivated Methyl Ester. From Organic Process Research & Development (2012), 16(12), 1967-1969.
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