hPGDS-IN-1
Based on 3 publication(s) in Google Scholar
hPGDS-IN-1 (Compound 2) is an hPGDS inhibitor with an IC50 of 12 nM (as measured by fluorescence polarization assay or EIA). hPGDS-IN-1 can be used in the research of allergic rhinitis and spinal cord neurons.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 1234708-04-3
- Formula: C22H20N6O3
- Molecular Weight:416.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) hPGDS-IN-1
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Biological Activity
hPGDS-IN-1 causes a significant reduction in the numbers of 5-HT-ir spinal cord neurons of 4 dpf zebrafish[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1234708-04-3
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Appearance Solid
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Molecular Weight 416.43
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Formula C22H20N6O3
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Color White to off-white
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SMILES
OC(C)(C)C1=NC(C2=CC(CNC(C(C=N3)=CN=C3C4=CC=CC=N4)=O)=CC=C2)=NO1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (3)
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Journal Impact Factor
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Most Recent
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Acta Pharm Sin B
DeepICER: A deep learning framework for predicting compound-induced gene expression profiles. [Abstract]2026 May;16(5):2947-2963. PMID: 42180546 -
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Solvent & Solubility
DMSO : 16.67 mg/mL (40.03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.4014 mL | 12.0068 mL | 24.0136 mL | 60.0341 mL |
| 5 mM | 0.4803 mL | 2.4014 mL | 4.8027 mL | 12.0068 mL | |
| 10 mM | 0.2401 mL | 1.2007 mL | 2.4014 mL | 6.0034 mL | |
| 15 mM | 0.1601 mL | 0.8005 mL | 1.6009 mL | 4.0023 mL | |
| 20 mM | 0.1201 mL | 0.6003 mL | 1.2007 mL | 3.0017 mL | |
| 25 mM | 0.0961 mL | 0.4803 mL | 0.9605 mL | 2.4014 mL | |
| 30 mM | 0.0800 mL | 0.4002 mL | 0.8005 mL | 2.0011 mL | |
| 40 mM | 0.0600 mL | 0.3002 mL | 0.6003 mL | 1.5009 mL |
hPGDS-IN-1 Related Classifications
HY-12791 Related Classifications
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