ECC-5004
ECC-5004 (Compound 1) is a GLP-1 receptor agonist with an EC50 of 0-20 nM. ECC-5004 exhibits strong inhibitory effects on OATP1B1, with an IC50 < 1 μM. ECC-5004 can be used to study diseases such as diabetes, obesity, and non-alcoholic fatty liver disease.
For research use only. We do not sell to patients.
- Formula: C48H48F2N10O5
- Molecular Weight:882.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| Species | Dose | Route | Cmax | AUC | F |
|---|---|---|---|---|---|
| Rat | 10 mg/kg | p.o. | 571 ng/mL | 4528 ng·h/mL | 10 % |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 882.96
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Formula C48H48F2N10O5
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SMILES
CC1=CC(N2N=C3CCN([C@H](C3=C2N4C=CN(C4=O)C5=C(C6=C(N(N=C6)C)C=C5)F)C)C(C7=C(N8C=CC([C@H]9CCOC(C)(C9)C)=CC8=C7)[C@]%10(C[C@@H]%10C)C%11=NOC(N%11)=O)=O)=CC(C)=C1F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ECC-5004 Related Classifications
HY-178767 Related Classifications
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