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Cat. No.: HY-184481

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DHPT-PEG2-C2-NH2

DHPT-PEG2-C2-NH2 (Compound 15) is a Target Protein Ligand-Linker Conjugate that contains an Htt ligand (HY-W040269) and a PROTAC linker (HY-W007545), and can recruit E3 ligases. JQ-1-Azidopropylamine is applicable for the synthesis of PROTAC HTT Degrader-1 (HY-184480).

For research use only. We do not sell to patients.

CAS No.: 2133002-45-4
Formula: C₂₀H₂₅N₃O₂S
Molecular Weight:371.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DHPT-PEG2-C2-NH2 Chemical Structure

CAS No.: 2133002-45-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 2133002-45-4
Molecular Weight 371.50
Formula C₂₀H₂₅N₃O₂S
SMILES

NCCOCCOCCNC(C=C1)=CC=C1C2=NC3=CC=C(C)C=C3S2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tomoshige S, et al. Discovery of Small Molecules that Induce the Degradation of Huntingtin. Angew Chem Int Ed Engl. 2017 Sep 11;56(38):11530-11533. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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