country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-E72101

Copy Link Print Information

Human CYP2E1, Reductase+b5

Human CYP2E1, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, which consists of human cytochrome P450 2E1, NADPH-P450 oxidoreductase (CPR), and cytochrome b5. Human CYP2E1 is a human cytochrome P450 subtype belonging to the CYP2 family, and also a major oxidase. Its expression is centered in human liver, and can be induced in the brain (neurons, astrocytes, cerebellar granule cells), lung and kidney.

Para uso exclusivo en investigación. No vendemos a pacientes.

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Human CYP2E1, Reductase+b5 Chemical Structure

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vivo

Human CYP2E1, Reductase+b5, via genetic suppression significantly ameliorates cerebral ischemia-reperfusion injury by reducing lesion volume (p < 0.005), neurological deficits, ROS production (1.5-fold reduction, p < 0.001), apoptosis, glial activation, inflammatory cytokine expression, and BBB leakage, while increasing protective 20-HETE levels by 41%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[Human CYP2E1, Reductase+b5]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Yu J, et al. Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury. Antioxidants (Basel, Switzerland). 2021 Jan 05;10(1):52. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Human CYP2E1, Reductase+b5

100 mg Obtener un presupuesto

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto

Amount: USD 0.00

Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

Human CYP2E1, Reductase+b5

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Human CYP2E1, Reductase+b5 Related Classifications

HY-E72101 Related Classifications

Bioz