Sgsm3 - small G protein signaling modulator 3 Gene

Also Known as Cip85; RUSC3; Rutbc3; 1810012I01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 105835

Summary

Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in positive regulation of protein catabolic process. Located in gap junction. Is expressed in several structures, including central nervous system; ear; ganglia; lung; and submandibular gland primordium. Orthologous to human SGSM3 (small G protein signaling modulator 3). [provided by Alliance of Genome Resources, Apr 2022]

Sgsm3 Products (2)

mRNA Protein Name
NM_001357669.1 NP_001344598.1 small G protein signaling modulator 3 isoform 2
NM_134091.2 NP_598852.3 small G protein signaling modulator 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15709751 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of protein catabolic process IDA
IDA: Inferred from direct assay
15709751 MGI
Cellular Component GO Annotation Evidence References Source
located in gap junction IDA
IDA: Inferred from direct assay
15709751 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small G protein signaling modulator 3

  • Cx43-interacting protein of 85-kDa

  • RUN and TBC1 domain-containing protein 3

Sgsm3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Sgsm3 Q8VCZ6 Gja1 Rattus norvegicus P08050
Imaging
15709751
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12815 SGSM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgsm3 NCBI NCBI:27352