AMG-076 free base
AMG-076 free base is an orally bioavailable and selective MCHR1 antagonist. AMG-076 free base results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice.
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- No. CAS: 693823-79-9
- Fòrmula: C26H33F3N2O2
- Peso molecular:462.55
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>5 μM
Compound: 11
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Inhibition of human Erg expressed in HEK293 cells assessed as rubidium efflux after 4 hrs by atomic absorbance spectrometric analysis
Inhibition of human Erg expressed in HEK293 cells assessed as rubidium efflux after 4 hrs by atomic absorbance spectrometric analysis
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[PMID: 22542010] |
Chemical Information
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No. CAS 693823-79-9
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Peso molecular 462.55
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Fòrmula C26H33F3N2O2
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SMILES
O=C(C1(CCN2CC[C@]3([H])CC(NC4=C5C=C(C(F)(F)F)C=C4)=C5[C@H](C)[C@@]3([H])C2)CCCCC1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMG-076 free base Related Classifications
HY-101699 Related Classifications
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