Fengabine
Fengabine is a GABAergic antidepressant agent. Fengabine can be used for the research of depression.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 80018-06-0
- Fòrmula: C17H17Cl2NO
- Peso molecular:322.23
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Fengabine (150 mg/kg; i.p) decreases the percentage of time spent. Fengabine (25~50 mg/kg; i.p.) reverses the deficit in learning the step-down avoidance task[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rats[1]
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Dosage:50 mg/kg
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Administration:I.p.
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Result:Prevented completely the learned helplessness induced by the unavoidable shock.
Chemical Information
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No. CAS 80018-06-0
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Peso molecular 322.23
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Fòrmula C17H17Cl2NO
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SMILES
OC1=CC=C(C=C1/C(C2=CC=CC=C2Cl)=N\CCCC)Cl
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Synonyms
SL 79229
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Ascalone V, et al. Determination of the GABAergic antidepressant drug fengabine and some of its metabolites in plasma by capillary gas chromatography with electron-capture detection. J Chromatogr. 1989;490(1):81-90. [Content Brief]
[2]. Lloyd KG, et al. Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. J Pharmacol Exp Ther. 1987;241(1):245-250. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fengabine Related Classifications
HY-123478 Related Classifications
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