Neu3 - neuraminidase 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50877

Summary

Enables exo-alpha-(2->3)-sialidase activity. Involved in ganglioside catabolic process. Located in early endosome membrane; external side of plasma membrane; and recycling endosome membrane. Is expressed in brain. Orthologous to human NEU3 (neuraminidase 3). [provided by Alliance of Genome Resources, Apr 2022]

Neu3 Products (1)

mRNA Protein Name
NM_016720.2 NP_057929.1 sialidase-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables exo-alpha-sialidase activity IDA
IDA: Inferred from direct assay
11696012 MGI
Biological Process GO Annotation Evidence Referencias Source
involved in ganglioside catabolic process IDA
IDA: Inferred from direct assay
11696012 MGI
Cellular Component GO Annotation Evidence Referencias Source
located in early endosome membrane IDA
IDA: Inferred from direct assay
17708748 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
17708748 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
14970224 MGI
located in recycling endosome membrane IDA
IDA: Inferred from direct assay
17708748 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialidase-3

  • N-acetyl-alpha-neuraminidase 3

  • Sialidase 3 (Membrane sialidase) (Ganglioside sialidase) (N-acetyl-alpha-neuraminidase 3)

  • ganglioside sialidase

  • membrane sialidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-125798 2,3-Dehydro-2-deoxy-N-acetylneuraminic acid Inhibitor ≥99.0% Unkown
HY-161943 NEU3-IN-1 98.74% Unkown
HY-RS09217 NEU3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22252 Neu3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28774 Neu3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neu3 NCBI NCBI:10825