Coasy - Coenzyme A synthase Gene

Also Known as Dpck; Ppat; Ukr1; 1300003G02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71743

Summary

This gene encodes the bifunctional protein coenzyme A (CoA) synthase which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this protein catalyzes the conversion of phosphopantetheine into dephospho-CoA while its dephospho-CoA kinase domain completes the final step by phosphorylating dephospho-CoA to form CoA. [provided by RefSeq, Apr 2015]

Coasy Products (1)

mRNA Protein Name
NM_001305982.1 NP_001292911.1 bifunctional coenzyme A synthase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables dephospho-CoA kinase activity IDA
IDA: Inferred from direct assay
11980892 MGI
enables pantetheine-phosphate adenylyltransferase activity IDA
IDA: Inferred from direct assay
11980892 MGI
enables pantetheine-phosphate adenylyltransferase activity IMP
IMP: Inferred from mutant phenotype
11980892 MGI
Biological Process GO Annotation Evidence Referencias Source
acts upstream of or within coenzyme A biosynthetic process IDA
IDA: Inferred from direct assay
11980892 MGI
involved in coenzyme A biosynthetic process IDA
IDA: Inferred from direct assay
11980892 MGI
Cellular Component GO Annotation Evidence Referencias Source
is active in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
14514684 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bifunctional coenzyme A synthase

  • 4'-phosphopantetheine adenylyltransferase and dephospho-CoA kinase

  • CoA synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS02946 COASY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180877 COASY modulator-1 / Unkown
HY-RS18993 Coasy Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25482 Coasy Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W1143867 4’-Phosphopantetheine Inhibitor 97.8% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Coasy NCBI NCBI:80347